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Proteomics

Proteomics

US 10,989,716 Methods of diagnosing acute rejection of a cardiac allograft in a subject using genomic expression profiling, proteomic expression profiling, or both on panels of nucleic acid markers and proteomic markers. The University of British Columbia (Vancouver, BC, Canada) McManus B, Ng R, Tebbutt S, Wilson-McManus J, Hollander Z, Lam K, Chen V, Dai…

US 10,989,716Methods of diagnosing acute rejection of a coronary allograft in an issue using genomic expression profiling, proteomic expression profiling, or both panels of nucleic acid markers and proteomic markers.The University of British Columbia (Vancouver, BC, Canada)McManus B, Ng R, Tebbutt S, Wilson-McManus J, Hollander Z, Lam K, Chen V, Dai D, Shannon C, Ignaszewski A, Balshaw R, McMaster R, Keown P4/27/2021US 10,948,497A proteomic expression platform to spot age-related sepsis risk. A semiquantitative plasma proteomics workflow was applied that incorporated tandem immunoaffinity depletion, iTRAQ tagging, strong cation exchange fractionation, and nanoflow liquid chromatography coupled to high resolution mass spectrometry to determine a protein profile which shows statistically significant differences in expression levels among patients with severe sepsis as a function of age.The University of Pittsburgh (Pittsburgh, PA, USA)Kellum JA, Cao Z, Angus D, Yende SP, Robinson RAS3/16/2021US 10,900,977Methods of determining whether a topic has an increased risk of experiencing memory impairment, comprising analyzing at least one plasma sample from the subject to ascertain a value of the topic’s proteomic profile and assessing the value of the topic’s proteomic profile with the value of a typical proteomic profile. A difference in the value of this subject’s proteomic profile from ordinary values indicates that the subject has an increased risk of experiencing memory impairment in comparison to an individual with normal values.Georgetown University (Washington, DC, USA), University of Rochester (Rochester, NY, USA)Federoff HJ, Fiandaca MS, Cheema AK, Mapstone ME, Zhong X1/26/2021US 10,895,574Methods and materials for use in research and clinical programs directed to cancers. Products include binding arrays; for example, hybridization or other special binding arrays such as genomic or proteomic microarrays.University of South Carolina (Columbia, SC, USA)Ramsdell AF1/19/2021US 1

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