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Immunotherapy promotes

SagA promotes immunotherapy response

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fight Immunotherapy

Immunotherapy May Help Fight Some Advanced Colon Cancers

By Robert PreidtHealthDay ReporterWEDNESDAY, Aug. 11, 2021 (HealthDay News) — Immunotherapy helped extend the lives of some patients with the most common type of advanced colon cancer, researchers report.The new findings are important, they noted, because immunotherapy doesn’t typically work against microsatellite stable (MSS) colon cancer. These patients have few treatment options once their disease…

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Immunotherapy T-Cell

CAR T-Cell Immunotherapy Rids Woman of Tough-to-Treat Lupus

By Amy Norton HealthDay ReporterTHURSDAY, Aug. 5, 2021 (HealthDay News) — In a first, researchers have used genetically tweaked immune system cells to send a woman’s severe lupus into remission.The treatment — called CAR T-cell therapy — is already approved in the United States for fighting certain cases of blood cancer. It involves removing a…

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building Immunotherapy

Immunotherapy: Building a bridge to a cure for type 1 diabetes

AbstractType 1 diabetes (T1D) is an autoimmune disease in which T cells attack and destroy the insulin-producing β cells in the pancreatic islets. Genetic and environmental factors increase T1D risk by compromising immune homeostasis. Although the discovery and use of insulin have transformed T1D treatment, insulin therapy does not change the underlying disease or fully…

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anti-obesity Immunotherapy

An anti-obesity immunotherapy?

SummaryEnergy storage is a crucial physiological process for all metazoans, the mechanisms of which are at least partially conserved across the animal kingdom. Lipid-storing adipocytes, the major constituent cell type of adipose tissues, are specialized for the storage of energy in the form of lipid triglycerides. Macrophages are an evolutionarily conserved immune cell population and…

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FIGHTs Immunotherapy

Immunotherapy Drug Fights Early-Stage Lung Cancer

By Dennis Thompson HealthDay ReporterTHURSDAY, May 20, 2021 (HealthDay News) — An immunotherapy drug is the first to significantly reduce the risk of cancer recurrence or death in people with early-stage lung cancer, researchers report.Atezolizumab reduced by 34% the risk of disease recurrence or death in a certain group of people with stage II to…

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Combination Immunotherapy

New combination immunotherapy plus ART expand innate cells Crucial to controlling HIV

ATLANTA – Yerkes National Primate Research Center researchers in collaboration with Institut Pasteur have determined a combination immunotherapy of Interleukin-21 (IL-21) and interferon alpha (IFN?) when added to antiviral therapy (ART) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models. This…

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doubling Immunotherapy

Doubling Down on Immunotherapy in Advanced Melanoma

Almost 30% of patients with advanced melanoma that progressed on prior checkpoint inhibition responded to pembrolizumab (Keytruda) plus low-dose ipilimumab (Yervoy), according to updated findings from a prospective trial. Overall, 20 of 70 patients had objective responses to the combination, including five complete responses. Median duration of response was 16.6 months, and the cohort had…